Scalable solvent-free production of liposomes

Screening of Lipid Composition for Scalable Fabrication of Solvent-Free Lipid Microarrays

Liquid microdroplet arrays on surfaces are a promising approach to the miniaturization of laboratory processes such as high-throughput screening. The fluid nature of these droplets poses unique challenges and opportunities in their fabrication and application, particularly for the scalable integration of multiple materials over large areas and immersion into cell culture solution. Here, we use ...

Solvent free permanganate oxidations

The oxidations of organic compounds by permanganate under solvent free conditions have been studied. Thiols and primary aromatic amines undergo oxidative coupling reactions to give disulfides and diazenes, respectively, sulfides are oxidized to sulfones, primary and secondary alcohols are converted to aldehydes and ketones, 1,4-diols and cyclic ethers give lactones and arenes are oxidized to th...

A Solvent Free Route to the Synthesis of Diaryl Sulfoxides

The solvent free route for the synthesis of diaryl sulfoxides from arenes and thionyl chloride in the presence of Lewis acids such as aluminum chloride and ferric chloride on silica gel are described.

Synthesis of Metallophthalocyanines Under Solvent Free Conditions Using Microwave Irradiation

Phthalocyanine complexes of Cu, Co, Ni, Fe, Zn, Pd, Pt and Ru have been synthesized from reaction between phthalonitrile and proper metal salts upon exposure to microwave irradiation under solvent-free conditions and considerably reduced reaction times.

CuCl2 Catalyzed Solvent-free One Pot Synthesis of Dihydropyrimidinones